b12 injection diarrhea Vitamin B-12 3000 mcg Injection, 100 mL My supplements while on Zepbound,

(2.1) If additional glycemic control is needed, increase the dosage in 2.5 mg increments after at least 4 weeks on the current dose

However, there are a few rare cases where this treatment is not recommended

Inform your doctor if you are a pregnant or breastfeeding mother or if you are suffering from any medical conditions such as liver or kidney disease

People who have had bariatric surgery Previous bariatric surgery, particularly gastric bypass, permanently alters the digestive anatomy in ways that reduce B12 absorption

Tom Biernacki, DPM Board-Certified Podiatrist Last updated April 6, 2026 Medically reviewed by Dr